Side-by-Side Comparison
Essential Vitamins & Minerals
Vitamin B1 (Thiamine) vs. Vitamin K1 (Phylloquinone)
Comparing 2 standards across 10 specifications. 10 key differences identified.
Comparing:
Vitamin B1 (Thiamine)
Vitamin K1 (Phylloquinone)
Vitamin B1 is a water-soluble pyrimidine/thiazole vitamin acting as the Thiamine Pyrophosphate (TPP) coenzyme in pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase, and transketolase. Adult RDA is 1.2 mg (men) / 1.1 mg (women) (no Upper Limit established).
Vitamin K1 is a fat-soluble naphthoquinone synthesized by photosynthetic plants. Adequate Intake (AI) is 120µg (men) / 90µg (women), acting as an essential cofactor for gamma-glutamyl carboxylase in blood clotting and osteocalcin bone mineralization.
Specification Comparison Table
10 Parameters| Parameter / Spec | ||
|---|---|---|
|
Nutrient Type
|
Water-Soluble Thiazole Vitamin | Fat-Soluble Naphthoquinone Vitamin |
|
Tolerable Upper Limit (UL)
|
None Established (Rapid renal clearance of excess) | None Established (No adverse effects reported) |
|
Chemical Forms
|
Thiamine Monophosphate, Thiamine Pyrophosphate (TPP / TDP, active coenzyme), Benfotiamine (Lipid-soluble synthetic) | Phylloquinone (K1 - Green Plants), Menaquinones (K2: MK-4, MK-7 - Ferments/Animal) |
|
Primary Biological Function
|
Pyruvate dehydrogenase complex (Links glycolysis to Krebs cycle), Transketolase (Pentose Phosphate Pathway), Myelin neurotransmission | Gamma-glutamyl carboxylase cofactor (Factors II, VII, IX, X), Osteocalcin carboxylation, Matrix Gla Protein (MGP) vascular calcification inhibitor |
|
Deficiency Condition
|
Beriberi (Wet beriberi: high-output heart failure; Dry beriberi: peripheral neuropathy), Wernicke-Korsakoff syndrome | Coagulopathy, Hemorrhage, Impaired bone density |
|
Top Whole Food Sources
|
Pork Tenderloin, Sunflower Seeds, Nutritional Yeast, Enriched Grains, Black Beans, Flaxseeds | Spinach, Kale, Broccoli, Brussels Sprouts, Natto (K2 MK-7), Parsley |
|
Adult RDA / RDI
|
1.2 mg / day (Men) / 1.1 mg / day (Women) (+0.3mg during pregnancy) | — |
|
Thermolability & Alcohol Interaction
|
Degraded by alkaline pH and high heat cooking; alcohol blocks intestinal active ThTr-1 transport | — |
|
Adult Adequate Intake (AI)
|
— | 120 µg / day (Men) / 90 µg / day (Women) |
|
Warfarin / Anticoagulant Interaction
|
— | Direct competitive antagonist to Coumadin/Warfarin (requires consistent daily intake) |
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