# item.guide
Side-by-Side Comparison Essential Vitamins & Minerals

Vitamin B1 (Thiamine) vs. Vitamin E (d-Alpha-Tocopherol)

Comparing 2 standards across 9 specifications. 9 key differences identified.

Comparing:
Vitamin B1 (Thiamine)
Vitamin E (d-Alpha-Tocopherol)
Vitamin B1 (Thiamine) →

Vitamin B1 is a water-soluble pyrimidine/thiazole vitamin acting as the Thiamine Pyrophosphate (TPP) coenzyme in pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase, and transketolase. Adult RDA is 1.2 mg (men) / 1.1 mg (women) (no Upper Limit established).

View full Vitamin B1 (Thiamine) spec sheet →
Vitamin E (d-Alpha-Tocopherol) →

Vitamin E is the principal fat-soluble peroxyl radical-scavenging antioxidant protecting cellular polyunsaturated membrane phospholipids. Adult RDA is 15 mg (22.4 IU) of d-alpha-tocopherol, with a Tolerable Upper Limit of 1,000 mg (1,500 IU)/day.

View full Vitamin E (d-Alpha-Tocopherol) spec sheet →

Specification Comparison Table

9 Parameters
Parameter / Spec
Vitamin B1 (Thiamine)
Vitamin E (d-Alpha-Tocopherol)
Nutrient Type
Water-Soluble Thiazole Vitamin Fat-Soluble Chromanol Lipophilic Vitamin
Adult RDA / RDI
1.2 mg / day (Men) / 1.1 mg / day (Women) (+0.3mg during pregnancy) 15 mg / day (22.4 IU) of 2R-alpha-tocopherol
Tolerable Upper Limit (UL)
None Established (Rapid renal clearance of excess) 1,000 mg / day (1,500 IU synthetic) (Excess impairs Vitamin K clotting cascade)
Chemical Forms
Thiamine Monophosphate, Thiamine Pyrophosphate (TPP / TDP, active coenzyme), Benfotiamine (Lipid-soluble synthetic) RRR-alpha-Tocopherol (Natural d-alpha), all-rac-alpha-Tocopherol (Synthetic dl-alpha), Gamma/Delta-Tocopherols
Primary Biological Function
Pyruvate dehydrogenase complex (Links glycolysis to Krebs cycle), Transketolase (Pentose Phosphate Pathway), Myelin neurotransmission Breaks lipid peroxidation chain in PUFA cell membranes, protects LDL from oxidative modification, maintains erythrocyte membrane integrity
Deficiency Condition
Beriberi (Wet beriberi: high-output heart failure; Dry beriberi: peripheral neuropathy), Wernicke-Korsakoff syndrome Hemolytic anemia, Spinocerebellar ataxia, Peripheral neuropathy, Loss of vibratory/proprioceptive sense
Top Whole Food Sources
Pork Tenderloin, Sunflower Seeds, Nutritional Yeast, Enriched Grains, Black Beans, Flaxseeds Wheat Germ Oil, Sunflower Seeds, Raw Almonds, Hazelnuts, Sunflower Oil, Spinach, Hass Avocado
Thermolability & Alcohol Interaction
Degraded by alkaline pH and high heat cooking; alcohol blocks intestinal active ThTr-1 transport —
Hepatic Alpha-TTP Specificity
— The liver secretes only alpha-tocopherol into VLDL via Alpha-Tocopherol Transfer Protein (alpha-TTP); other tocopherols are degraded in bile

Other Alternatives to Compare

Compare Vitamin B1 (Thiamine) vs. Calcium (Elemental Ca) → Compare Vitamin B1 (Thiamine) vs. Iodine (Elemental I) → Compare Vitamin B1 (Thiamine) vs. Iron (Heme & Non-Heme) → Compare Vitamin B1 (Thiamine) vs. Magnesium (Elemental Mg) → Compare Vitamin B1 (Thiamine) vs. Potassium (Elemental K) → Compare Vitamin B1 (Thiamine) vs. Selenium (Elemental Se) → Compare Vitamin B1 (Thiamine) vs. Sodium (Elemental Na) → Compare Vitamin B1 (Thiamine) vs. Vitamin A (Retinol & Beta-Carotene) → Compare Vitamin B1 (Thiamine) vs. Vitamin B12 (Cobalamin) → Compare Vitamin B1 (Thiamine) vs. Vitamin B2 (Riboflavin) → Compare Vitamin B1 (Thiamine) vs. Vitamin B3 (Niacin / Nicotinic Acid & Nicotinamide) → Compare Vitamin B1 (Thiamine) vs. Vitamin B5 (Pantothenic Acid) → Compare Vitamin B1 (Thiamine) vs. Vitamin B6 (Pyridoxal 5'-Phosphate / PLP) → Compare Vitamin B1 (Thiamine) vs. Vitamin B7 (Biotin / Vitamin H) → Compare Vitamin B1 (Thiamine) vs. Vitamin B9 (Folate & Folic Acid) → Compare Vitamin B1 (Thiamine) vs. Vitamin C (L-Ascorbic Acid) → Compare Vitamin B1 (Thiamine) vs. Vitamin D3 (Cholecalciferol) → Compare Vitamin B1 (Thiamine) vs. Vitamin K1 (Phylloquinone) → Compare Vitamin B1 (Thiamine) vs. Zinc (Elemental Zn) →