# item.guide
Side-by-Side Comparison Essential Vitamins & Minerals

Vitamin B1 (Thiamine) vs. Vitamin B2 (Riboflavin)

Comparing 2 standards across 9 specifications. 9 key differences identified.

Comparing:
Vitamin B1 (Thiamine)
Vitamin B2 (Riboflavin)
Vitamin B1 (Thiamine) →

Vitamin B1 is a water-soluble pyrimidine/thiazole vitamin acting as the Thiamine Pyrophosphate (TPP) coenzyme in pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase, and transketolase. Adult RDA is 1.2 mg (men) / 1.1 mg (women) (no Upper Limit established).

View full Vitamin B1 (Thiamine) spec sheet →
Vitamin B2 (Riboflavin) →

Vitamin B2 is an essential water-soluble isoalloxazine vitamin serving as the core structural component of Flavin Mononucleotide (FMN) and Flavin Adenine Dinucleotide (FAD) coenzymes in cellular redox respiration. Adult RDA is 1.3 mg (men) / 1.1 mg (women).

View full Vitamin B2 (Riboflavin) spec sheet →

Specification Comparison Table

9 Parameters
Parameter / Spec
Vitamin B1 (Thiamine)
Vitamin B2 (Riboflavin)
Nutrient Type
Water-Soluble Thiazole Vitamin Water-Soluble Isoalloxazine Vitamin
Adult RDA / RDI
1.2 mg / day (Men) / 1.1 mg / day (Women) (+0.3mg during pregnancy) 1.3 mg / day (Men) / 1.1 mg / day (Women)
Tolerable Upper Limit (UL)
None Established (Rapid renal clearance of excess) None Established (Saturates intestinal absorption at ~27mg; excreted as harmless bright yellow urine)
Chemical Forms
Thiamine Monophosphate, Thiamine Pyrophosphate (TPP / TDP, active coenzyme), Benfotiamine (Lipid-soluble synthetic) Riboflavin, Riboflavin-5'-Phosphate (FMN), Flavin Adenine Dinucleotide (FAD)
Primary Biological Function
Pyruvate dehydrogenase complex (Links glycolysis to Krebs cycle), Transketolase (Pentose Phosphate Pathway), Myelin neurotransmission Complex I and Complex II mitochondrial electron transport chain cytochromes, Glutathione Reductase, B6/Folate activation
Deficiency Condition
Beriberi (Wet beriberi: high-output heart failure; Dry beriberi: peripheral neuropathy), Wernicke-Korsakoff syndrome Ariboflavinosis (Angular cheilitis / cracked lip corners, glossitis / magenta tongue, seborrheic dermatitis)
Top Whole Food Sources
Pork Tenderloin, Sunflower Seeds, Nutritional Yeast, Enriched Grains, Black Beans, Flaxseeds Beef Liver, Dairy Milk, Greek Yogurt, Eggs, Almonds, Portobello Mushrooms, Spinach
Thermolability & Alcohol Interaction
Degraded by alkaline pH and high heat cooking; alcohol blocks intestinal active ThTr-1 transport —
Photodegradation Vulnerability
— Extremely light-sensitive (dairy milk stored in clear glass loses 50% riboflavin within 2 hours of sunlight exposure)

Other Alternatives to Compare

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