# item.guide

Vitamin B2 (Riboflavin)

Essential Vitamins & Minerals · 8 specs

Direct Answer

Vitamin B2 is an essential water-soluble isoalloxazine vitamin serving as the core structural component of Flavin Mononucleotide (FMN) and Flavin Adenine Dinucleotide (FAD) coenzymes in cellular redox respiration. Adult RDA is 1.3 mg (men) / 1.1 mg (women).

Source: NIH ODS / EFSA · Last reviewed Aug 28, 2026

Specs

Nutrient Type Water-Soluble Isoalloxazine Vitamin
Adult RDA / RDI 1.3 mg / day (Men) / 1.1 mg / day (Women)
Tolerable Upper Limit (UL) None Established (Saturates intestinal absorption at ~27mg; excreted as harmless bright yellow urine)
Chemical Forms Riboflavin, Riboflavin-5'-Phosphate (FMN), Flavin Adenine Dinucleotide (FAD)
Primary Biological Function Complex I and Complex II mitochondrial electron transport chain cytochromes, Glutathione Reductase, B6/Folate activation
Deficiency Condition Ariboflavinosis (Angular cheilitis / cracked lip corners, glossitis / magenta tongue, seborrheic dermatitis)
Top Whole Food Sources Beef Liver, Dairy Milk, Greek Yogurt, Eggs, Almonds, Portobello Mushrooms, Spinach
Photodegradation Vulnerability Extremely light-sensitive (dairy milk stored in clear glass loses 50% riboflavin within 2 hours of sunlight exposure)

FAD & Glutathione Antioxidant Regeneration

Riboflavin in the form of FAD is the mandatory prosthetic coenzyme for glutathione reductase, regenerating reduced glutathione (GSH) to defend cells against reactive oxygen species.

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