Selenium (Elemental Se) vs. Vitamin B2 (Riboflavin)
Comparing 2 standards across 9 specifications. 9 key differences identified.
Selenium is an essential trace element incorporated as Selenocysteine (the 21st amino acid) into 25 human selenoproteins including Glutathione Peroxidases (GPx) and Iodothyronine Deiodinases (T4->T3 conversion). Adult RDA is 55 µg, with a Tolerable Upper Limit of 400 µg/day.
Vitamin B2 is an essential water-soluble isoalloxazine vitamin serving as the core structural component of Flavin Mononucleotide (FMN) and Flavin Adenine Dinucleotide (FAD) coenzymes in cellular redox respiration. Adult RDA is 1.3 mg (men) / 1.1 mg (women).
Specification Comparison Table
9 Parameters| Parameter / Spec | ||
|---|---|---|
|
Nutrient Type
|
Essential Trace Element | Water-Soluble Isoalloxazine Vitamin |
|
Adult RDA / RDI
|
55 µg / day (60 µg pregnancy, 70 µg lactation) | 1.3 mg / day (Men) / 1.1 mg / day (Women) |
|
Tolerable Upper Limit (UL)
|
400 µg / day (Avoid selenosis / garlic breath, hair/nail brittleness) | None Established (Saturates intestinal absorption at ~27mg; excreted as harmless bright yellow urine) |
|
Chemical Forms
|
Selenomethionine (Plant organic), Selenocysteine (Animal selenoprotein), Sodium Selenite / Selenate (Inorganic) | Riboflavin, Riboflavin-5'-Phosphate (FMN), Flavin Adenine Dinucleotide (FAD) |
|
Primary Biological Function
|
Glutathione Peroxidase (GPx1-4) lipid hydroperoxide neutralization, Iodothyronine Deiodinases (Converts thyroid T4 into active T3), Thioredoxin Reductase (TXNRD) | Complex I and Complex II mitochondrial electron transport chain cytochromes, Glutathione Reductase, B6/Folate activation |
|
Deficiency Condition
|
Keshan Disease (Endemic juvenile cardiomyopathy), Kashin-Beck Disease (Deforming osteoarthropathy), Impaired thyroid metabolism | Ariboflavinosis (Angular cheilitis / cracked lip corners, glossitis / magenta tongue, seborrheic dermatitis) |
|
Top Whole Food Sources
|
Brazil Nuts (1 single nut provides ~70–90µg / 130–160% RDA), Eastern Oysters, Yellowfin Tuna, Halibut, Sardines, Beef Liver, Eggs | Beef Liver, Dairy Milk, Greek Yogurt, Eggs, Almonds, Portobello Mushrooms, Spinach |
|
Soil Selenium Geographical Variability
|
Plant selenium reflects regional soil content; volcanic soils (South America, Great Plains) are rich, while parts of China, Scandinavia, and New Zealand are depleted | — |
|
Photodegradation Vulnerability
|
— | Extremely light-sensitive (dairy milk stored in clear glass loses 50% riboflavin within 2 hours of sunlight exposure) |