# item.guide
Side-by-Side Comparison Essential Vitamins & Minerals

Selenium (Elemental Se) vs. Vitamin B2 (Riboflavin)

Comparing 2 standards across 9 specifications. 9 key differences identified.

Comparing:
Selenium (Elemental Se)
Vitamin B2 (Riboflavin)

Selenium is an essential trace element incorporated as Selenocysteine (the 21st amino acid) into 25 human selenoproteins including Glutathione Peroxidases (GPx) and Iodothyronine Deiodinases (T4->T3 conversion). Adult RDA is 55 µg, with a Tolerable Upper Limit of 400 µg/day.

View full Selenium (Elemental Se) spec sheet →

Vitamin B2 is an essential water-soluble isoalloxazine vitamin serving as the core structural component of Flavin Mononucleotide (FMN) and Flavin Adenine Dinucleotide (FAD) coenzymes in cellular redox respiration. Adult RDA is 1.3 mg (men) / 1.1 mg (women).

View full Vitamin B2 (Riboflavin) spec sheet →

Specification Comparison Table

9 Parameters
Parameter / Spec
Nutrient Type
Essential Trace Element Water-Soluble Isoalloxazine Vitamin
Adult RDA / RDI
55 µg / day (60 µg pregnancy, 70 µg lactation) 1.3 mg / day (Men) / 1.1 mg / day (Women)
Tolerable Upper Limit (UL)
400 µg / day (Avoid selenosis / garlic breath, hair/nail brittleness) None Established (Saturates intestinal absorption at ~27mg; excreted as harmless bright yellow urine)
Chemical Forms
Selenomethionine (Plant organic), Selenocysteine (Animal selenoprotein), Sodium Selenite / Selenate (Inorganic) Riboflavin, Riboflavin-5'-Phosphate (FMN), Flavin Adenine Dinucleotide (FAD)
Primary Biological Function
Glutathione Peroxidase (GPx1-4) lipid hydroperoxide neutralization, Iodothyronine Deiodinases (Converts thyroid T4 into active T3), Thioredoxin Reductase (TXNRD) Complex I and Complex II mitochondrial electron transport chain cytochromes, Glutathione Reductase, B6/Folate activation
Deficiency Condition
Keshan Disease (Endemic juvenile cardiomyopathy), Kashin-Beck Disease (Deforming osteoarthropathy), Impaired thyroid metabolism Ariboflavinosis (Angular cheilitis / cracked lip corners, glossitis / magenta tongue, seborrheic dermatitis)
Top Whole Food Sources
Brazil Nuts (1 single nut provides ~70–90µg / 130–160% RDA), Eastern Oysters, Yellowfin Tuna, Halibut, Sardines, Beef Liver, Eggs Beef Liver, Dairy Milk, Greek Yogurt, Eggs, Almonds, Portobello Mushrooms, Spinach
Soil Selenium Geographical Variability
Plant selenium reflects regional soil content; volcanic soils (South America, Great Plains) are rich, while parts of China, Scandinavia, and New Zealand are depleted
Photodegradation Vulnerability
Extremely light-sensitive (dairy milk stored in clear glass loses 50% riboflavin within 2 hours of sunlight exposure)