# item.guide
Side-by-Side Comparison Essential Vitamins & Minerals

Selenium (Elemental Se) vs. Vitamin B1 (Thiamine)

Comparing 2 standards across 9 specifications. 9 key differences identified.

Comparing:
Selenium (Elemental Se)
Vitamin B1 (Thiamine)

Selenium is an essential trace element incorporated as Selenocysteine (the 21st amino acid) into 25 human selenoproteins including Glutathione Peroxidases (GPx) and Iodothyronine Deiodinases (T4->T3 conversion). Adult RDA is 55 µg, with a Tolerable Upper Limit of 400 µg/day.

View full Selenium (Elemental Se) spec sheet →

Vitamin B1 is a water-soluble pyrimidine/thiazole vitamin acting as the Thiamine Pyrophosphate (TPP) coenzyme in pyruvate dehydrogenase, alpha-ketoglutarate dehydrogenase, and transketolase. Adult RDA is 1.2 mg (men) / 1.1 mg (women) (no Upper Limit established).

View full Vitamin B1 (Thiamine) spec sheet →

Specification Comparison Table

9 Parameters
Parameter / Spec
Nutrient Type
Essential Trace Element Water-Soluble Thiazole Vitamin
Adult RDA / RDI
55 µg / day (60 µg pregnancy, 70 µg lactation) 1.2 mg / day (Men) / 1.1 mg / day (Women) (+0.3mg during pregnancy)
Tolerable Upper Limit (UL)
400 µg / day (Avoid selenosis / garlic breath, hair/nail brittleness) None Established (Rapid renal clearance of excess)
Chemical Forms
Selenomethionine (Plant organic), Selenocysteine (Animal selenoprotein), Sodium Selenite / Selenate (Inorganic) Thiamine Monophosphate, Thiamine Pyrophosphate (TPP / TDP, active coenzyme), Benfotiamine (Lipid-soluble synthetic)
Primary Biological Function
Glutathione Peroxidase (GPx1-4) lipid hydroperoxide neutralization, Iodothyronine Deiodinases (Converts thyroid T4 into active T3), Thioredoxin Reductase (TXNRD) Pyruvate dehydrogenase complex (Links glycolysis to Krebs cycle), Transketolase (Pentose Phosphate Pathway), Myelin neurotransmission
Deficiency Condition
Keshan Disease (Endemic juvenile cardiomyopathy), Kashin-Beck Disease (Deforming osteoarthropathy), Impaired thyroid metabolism Beriberi (Wet beriberi: high-output heart failure; Dry beriberi: peripheral neuropathy), Wernicke-Korsakoff syndrome
Top Whole Food Sources
Brazil Nuts (1 single nut provides ~70–90µg / 130–160% RDA), Eastern Oysters, Yellowfin Tuna, Halibut, Sardines, Beef Liver, Eggs Pork Tenderloin, Sunflower Seeds, Nutritional Yeast, Enriched Grains, Black Beans, Flaxseeds
Soil Selenium Geographical Variability
Plant selenium reflects regional soil content; volcanic soils (South America, Great Plains) are rich, while parts of China, Scandinavia, and New Zealand are depleted
Thermolability & Alcohol Interaction
Degraded by alkaline pH and high heat cooking; alcohol blocks intestinal active ThTr-1 transport