# item.guide
Side-by-Side Comparison Essential Vitamins & Minerals

Iodine (Elemental I) vs. Vitamin B2 (Riboflavin)

Comparing 2 standards across 9 specifications. 9 key differences identified.

Comparing:
Iodine (Elemental I)
Vitamin B2 (Riboflavin)

Iodine is an essential halogen trace element required exclusively as an essential structural component of thyroid hormones thyroxine (T4) and triiodothyronine (T3), regulating metabolic rate, cellular respiration, and fetal neurodevelopment. Adult RDA is 150 µg, with an Upper Limit of 1,100 µg/day.

View full Iodine (Elemental I) spec sheet →

Vitamin B2 is an essential water-soluble isoalloxazine vitamin serving as the core structural component of Flavin Mononucleotide (FMN) and Flavin Adenine Dinucleotide (FAD) coenzymes in cellular redox respiration. Adult RDA is 1.3 mg (men) / 1.1 mg (women).

View full Vitamin B2 (Riboflavin) spec sheet →

Specification Comparison Table

9 Parameters
Parameter / Spec
Nutrient Type
Essential Trace Halogen Element Water-Soluble Isoalloxazine Vitamin
Adult RDA / RDI
150 µg / day (220 µg pregnancy / 290 µg lactation) 1.3 mg / day (Men) / 1.1 mg / day (Women)
Tolerable Upper Limit (UL)
1,100 µg / day (Avoid Wolff-Chaikoff thyroid autoregulatory shutdown) None Established (Saturates intestinal absorption at ~27mg; excreted as harmless bright yellow urine)
Chemical Forms
Iodide (I- / Potassium Iodide KI, Potassium Iodate KIO3 in iodized salt), Molecular Iodine Riboflavin, Riboflavin-5'-Phosphate (FMN), Flavin Adenine Dinucleotide (FAD)
Primary Biological Function
Constituent of Thyroxine (T4, 4 iodine atoms / 65% by weight) and Triiodothyronine (T3, 3 iodine atoms / 59% by weight) Complex I and Complex II mitochondrial electron transport chain cytochromes, Glutathione Reductase, B6/Folate activation
Deficiency Condition
Endemic Goiter (Compensatory thyroid enlargement), Congenital Hypothyroidism / Cretinism (Permanent neurodevelopmental impairment), Maternal miscarriages Ariboflavinosis (Angular cheilitis / cracked lip corners, glossitis / magenta tongue, seborrheic dermatitis)
Top Whole Food Sources
Kombu Kelp, Nori Seaweed, Atlantic Cod, Eastern Oysters, Iodized Table Salt, Greek Yogurt, Dairy Milk, Eggs Beef Liver, Dairy Milk, Greek Yogurt, Eggs, Almonds, Portobello Mushrooms, Spinach
Iodized Salt Public Health Impact
Universal salt iodization (45–75 mg KI / kg salt) is hailed as one of the greatest global public health achievements, eradicating cretinism worldwide
Photodegradation Vulnerability
Extremely light-sensitive (dairy milk stored in clear glass loses 50% riboflavin within 2 hours of sunlight exposure)