# item.guide
Side-by-Side Comparison Essential Vitamins & Minerals

Iodine (Elemental I) vs. Iron (Heme & Non-Heme)

Comparing 2 standards across 9 specifications. 9 key differences identified.

Comparing:
Iodine (Elemental I)
Iron (Heme & Non-Heme)

Iodine is an essential halogen trace element required exclusively as an essential structural component of thyroid hormones thyroxine (T4) and triiodothyronine (T3), regulating metabolic rate, cellular respiration, and fetal neurodevelopment. Adult RDA is 150 µg, with an Upper Limit of 1,100 µg/day.

View full Iodine (Elemental I) spec sheet →

Iron is an essential redox trace element central to hemoglobin oxygen transport, myoglobin storage, and mitochondrial electron transport chain cytochromes. Adult RDA is 8mg (men/post-menopausal women) / 18mg (pre-menopausal women), with a Tolerable Upper Limit of 45mg/day.

View full Iron (Heme & Non-Heme) spec sheet →

Specification Comparison Table

9 Parameters
Parameter / Spec
Nutrient Type
Essential Trace Halogen Element Essential Trace Mineral
Adult RDA / RDI
150 µg / day (220 µg pregnancy / 290 µg lactation) 8 mg (Men) / 18 mg (Women 19–50) / 27 mg (Pregnancy)
Tolerable Upper Limit (UL)
1,100 µg / day (Avoid Wolff-Chaikoff thyroid autoregulatory shutdown) 45 mg / day (Hemochromatosis / Fenton reaction oxidative stress)
Chemical Forms
Iodide (I- / Potassium Iodide KI, Potassium Iodate KIO3 in iodized salt), Molecular Iodine Heme Iron (Fe2+ Porphyrin - Animal), Non-Heme Iron (Fe3+ Ferric / Fe2+ Ferrous - Plants/Supplements)
Primary Biological Function
Constituent of Thyroxine (T4, 4 iodine atoms / 65% by weight) and Triiodothyronine (T3, 3 iodine atoms / 59% by weight) Hemoglobin O2 transport, Myoglobin O2 storage, Cytochrome c electron transport, Catalase
Deficiency Condition
Endemic Goiter (Compensatory thyroid enlargement), Congenital Hypothyroidism / Cretinism (Permanent neurodevelopmental impairment), Maternal miscarriages Microcytic Hypochromic Anemia, Severe fatigue, Restless legs syndrome, Pica
Top Whole Food Sources
Kombu Kelp, Nori Seaweed, Atlantic Cod, Eastern Oysters, Iodized Table Salt, Greek Yogurt, Dairy Milk, Eggs Beef Liver, Oysters, Duck Breast, Beef Ribeye, Lentils, Spinach, Dark Chocolate
Iodized Salt Public Health Impact
Universal salt iodization (45–75 mg KI / kg salt) is hailed as one of the greatest global public health achievements, eradicating cretinism worldwide
Bioavailability Difference
Heme: 15–35% absorption (uninhibited); Non-Heme: 2–20% (inhibited by phytates/calcium, boosted by Vitamin C)