# item.guide
Side-by-Side Comparison Essential Vitamins & Minerals

Iodine (Elemental I) vs. Sodium (Elemental Na)

Comparing 2 standards across 11 specifications. 11 key differences identified.

Comparing:
Iodine (Elemental I)
Sodium (Elemental Na)

Iodine is an essential halogen trace element required exclusively as an essential structural component of thyroid hormones thyroxine (T4) and triiodothyronine (T3), regulating metabolic rate, cellular respiration, and fetal neurodevelopment. Adult RDA is 150 µg, with an Upper Limit of 1,100 µg/day.

View full Iodine (Elemental I) spec sheet →

Sodium is the principal extracellular cation (135–145 mEq/L extracellular), maintaining extracellular fluid volume, plasma osmolality, and driving secondary active transport. Adequate Intake (AI) is 1,500 mg/day, with a Chronic Disease Risk Reduction (CDRR) limit of 2,300 mg/day.

View full Sodium (Elemental Na) spec sheet →

Specification Comparison Table

11 Parameters
Parameter / Spec
Nutrient Type
Essential Trace Halogen Element Essential Macromineral / Major Extracellular Electrolyte
Chemical Forms
Iodide (I- / Potassium Iodide KI, Potassium Iodate KIO3 in iodized salt), Molecular Iodine Sodium Chloride (NaCl, 39.3% Na by weight), Monosodium Glutamate (MSG, 12.3% Na), Sodium Bicarbonate (27.4% Na)
Primary Biological Function
Constituent of Thyroxine (T4, 4 iodine atoms / 65% by weight) and Triiodothyronine (T3, 3 iodine atoms / 59% by weight) Extracellular fluid osmolality maintenance, Blood pressure / volume homeostasis, Action potential depolarization (voltage-gated Na+ channels), SGLT1 glucose cotransport
Deficiency Condition
Endemic Goiter (Compensatory thyroid enlargement), Congenital Hypothyroidism / Cretinism (Permanent neurodevelopmental impairment), Maternal miscarriages Hyponatremia (Serum Na+ < 135 mmol/L): Cerebral edema, Nausea, Muscle cramps, Seizures, Coma (often exercise-associated from over-hydration)
Top Whole Food Sources
Kombu Kelp, Nori Seaweed, Atlantic Cod, Eastern Oysters, Iodized Table Salt, Greek Yogurt, Dairy Milk, Eggs Table Salt (NaCl), Cured Bacon, Soy Sauce, Parmigiano-Reggiano, Pickles, Olives, Bread (Processed food accounts for 70% of intake)
Adult RDA / RDI
150 µg / day (220 µg pregnancy / 290 µg lactation)
Tolerable Upper Limit (UL)
1,100 µg / day (Avoid Wolff-Chaikoff thyroid autoregulatory shutdown)
Iodized Salt Public Health Impact
Universal salt iodization (45–75 mg KI / kg salt) is hailed as one of the greatest global public health achievements, eradicating cretinism worldwide
Adult Adequate Intake (AI)
1,500 mg / day (Equal to 3.8 g table salt NaCl)
Chronic Disease Limit (CDRR)
2,300 mg / day (Equal to 5.8 g table salt / 1 level teaspoon)
Renal Renin-Angiotensin System
Juxtaglomerular apparatus senses low tubular sodium/pressure, secreting renin to stimulate aldosterone and renal Na+ reabsorption