Vitamin C (L-Ascorbic Acid) vs. Vitamin K1 (Phylloquinone)
Comparing 2 standards across 10 specifications. 10 key differences identified.
Vitamin C is a water-soluble electron donor and antioxidant essential for collagen proline/lysine hydroxylation, non-heme iron absorption, and immune phagocyte function. Adult RDA is 90mg (men) / 75mg (women), with a Tolerable Upper Limit of 2,000mg/day.
Vitamin K1 is a fat-soluble naphthoquinone synthesized by photosynthetic plants. Adequate Intake (AI) is 120µg (men) / 90µg (women), acting as an essential cofactor for gamma-glutamyl carboxylase in blood clotting and osteocalcin bone mineralization.
Specification Comparison Table
10 Parameters| Parameter / Spec | ||
|---|---|---|
|
Nutrient Type
|
Water-Soluble Vitamin | Fat-Soluble Naphthoquinone Vitamin |
|
Tolerable Upper Limit (UL)
|
2,000 mg / day (Avoid osmotic diarrhea) | None Established (No adverse effects reported) |
|
Chemical Forms
|
L-Ascorbic Acid, Sodium Ascorbate, Calcium Ascorbate | Phylloquinone (K1 - Green Plants), Menaquinones (K2: MK-4, MK-7 - Ferments/Animal) |
|
Primary Biological Function
|
Prolyl/Lysyl Hydroxylase cofactor (Collagen), ROS scavenger, Carnitine synthesis | Gamma-glutamyl carboxylase cofactor (Factors II, VII, IX, X), Osteocalcin carboxylation, Matrix Gla Protein (MGP) vascular calcification inhibitor |
|
Deficiency Condition
|
Scurvy (Collagen breakdown, capillary fragility, impaired wound healing) | Coagulopathy, Hemorrhage, Impaired bone density |
|
Top Whole Food Sources
|
Red Bell Pepper, Strawberries, Citrus, Kiwi, Broccoli, Brussels Sprouts | Spinach, Kale, Broccoli, Brussels Sprouts, Natto (K2 MK-7), Parsley |
|
Adult RDA / RDI
|
90 mg (Men) / 75 mg (Women) (+35mg for smokers) | — |
|
Thermolability
|
Highly heat- and oxygen-sensitive (degrades rapidly with prolonged boiling) | — |
|
Adult Adequate Intake (AI)
|
— | 120 µg / day (Men) / 90 µg / day (Women) |
|
Warfarin / Anticoagulant Interaction
|
— | Direct competitive antagonist to Coumadin/Warfarin (requires consistent daily intake) |