Vitamin C (L-Ascorbic Acid) vs. Vitamin D3 (Cholecalciferol)
Comparing 2 standards across 9 specifications. 9 key differences identified.
Vitamin C is a water-soluble electron donor and antioxidant essential for collagen proline/lysine hydroxylation, non-heme iron absorption, and immune phagocyte function. Adult RDA is 90mg (men) / 75mg (women), with a Tolerable Upper Limit of 2,000mg/day.
Vitamin D3 is a secosteroid prohormone synthesized endogenously in skin via solar UVB irradiation of 7-dehydrocholesterol. Adult RDA is 600–800 IU (15–20µg), with a Tolerable Upper Limit of 4,000 IU (100µg)/day, regulating systemic calcium absorption and immune gene expression.
Specification Comparison Table
9 Parameters| Parameter / Spec | ||
|---|---|---|
|
Nutrient Type
|
Water-Soluble Vitamin | Fat-Soluble Secosteroid Prohormone |
|
Adult RDA / RDI
|
90 mg (Men) / 75 mg (Women) (+35mg for smokers) | 600 – 800 IU / day (15 – 20 µg) |
|
Tolerable Upper Limit (UL)
|
2,000 mg / day (Avoid osmotic diarrhea) | 4,000 IU / day (100 µg) (Endocrine Society: up to 10,000 IU safe) |
|
Chemical Forms
|
L-Ascorbic Acid, Sodium Ascorbate, Calcium Ascorbate | Cholecalciferol (D3 - Animal/Lichen), Ergocalciferol (D2 - Fungi) |
|
Primary Biological Function
|
Prolyl/Lysyl Hydroxylase cofactor (Collagen), ROS scavenger, Carnitine synthesis | Calcitriol receptor (VDR) activation, intestinal calcium/phosphorus absorption, antimicrobial peptide synthesis |
|
Deficiency Condition
|
Scurvy (Collagen breakdown, capillary fragility, impaired wound healing) | Rickets (children), Osteomalacia (adults), Immune dysregulation |
|
Top Whole Food Sources
|
Red Bell Pepper, Strawberries, Citrus, Kiwi, Broccoli, Brussels Sprouts | Sunlight UVB, Atlantic Salmon, Sardines, Egg Yolk, Fortified Milk |
|
Thermolability
|
Highly heat- and oxygen-sensitive (degrades rapidly with prolonged boiling) | — |
|
Target Serum 25(OH)D Level
|
— | 30 – 50 ng / mL (75 – 125 nmol / L) |