# item.guide
Side-by-Side Comparison Essential Vitamins & Minerals

Vitamin C (L-Ascorbic Acid) vs. Vitamin E (d-Alpha-Tocopherol)

Comparing 2 standards across 9 specifications. 9 key differences identified.

Comparing:
Vitamin C (L-Ascorbic Acid)
Vitamin E (d-Alpha-Tocopherol)

Vitamin C is a water-soluble electron donor and antioxidant essential for collagen proline/lysine hydroxylation, non-heme iron absorption, and immune phagocyte function. Adult RDA is 90mg (men) / 75mg (women), with a Tolerable Upper Limit of 2,000mg/day.

View full Vitamin C (L-Ascorbic Acid) spec sheet →

Vitamin E is the principal fat-soluble peroxyl radical-scavenging antioxidant protecting cellular polyunsaturated membrane phospholipids. Adult RDA is 15 mg (22.4 IU) of d-alpha-tocopherol, with a Tolerable Upper Limit of 1,000 mg (1,500 IU)/day.

View full Vitamin E (d-Alpha-Tocopherol) spec sheet →

Specification Comparison Table

9 Parameters
Parameter / Spec
Nutrient Type
Water-Soluble Vitamin Fat-Soluble Chromanol Lipophilic Vitamin
Adult RDA / RDI
90 mg (Men) / 75 mg (Women) (+35mg for smokers) 15 mg / day (22.4 IU) of 2R-alpha-tocopherol
Tolerable Upper Limit (UL)
2,000 mg / day (Avoid osmotic diarrhea) 1,000 mg / day (1,500 IU synthetic) (Excess impairs Vitamin K clotting cascade)
Chemical Forms
L-Ascorbic Acid, Sodium Ascorbate, Calcium Ascorbate RRR-alpha-Tocopherol (Natural d-alpha), all-rac-alpha-Tocopherol (Synthetic dl-alpha), Gamma/Delta-Tocopherols
Primary Biological Function
Prolyl/Lysyl Hydroxylase cofactor (Collagen), ROS scavenger, Carnitine synthesis Breaks lipid peroxidation chain in PUFA cell membranes, protects LDL from oxidative modification, maintains erythrocyte membrane integrity
Deficiency Condition
Scurvy (Collagen breakdown, capillary fragility, impaired wound healing) Hemolytic anemia, Spinocerebellar ataxia, Peripheral neuropathy, Loss of vibratory/proprioceptive sense
Top Whole Food Sources
Red Bell Pepper, Strawberries, Citrus, Kiwi, Broccoli, Brussels Sprouts Wheat Germ Oil, Sunflower Seeds, Raw Almonds, Hazelnuts, Sunflower Oil, Spinach, Hass Avocado
Thermolability
Highly heat- and oxygen-sensitive (degrades rapidly with prolonged boiling)
Hepatic Alpha-TTP Specificity
The liver secretes only alpha-tocopherol into VLDL via Alpha-Tocopherol Transfer Protein (alpha-TTP); other tocopherols are degraded in bile