# item.guide
Side-by-Side Comparison Essential Vitamins & Minerals

Iodine (Elemental I) vs. Vitamin K1 (Phylloquinone)

Comparing 2 standards across 10 specifications. 10 key differences identified.

Comparing:
Iodine (Elemental I)
Vitamin K1 (Phylloquinone)

Iodine is an essential halogen trace element required exclusively as an essential structural component of thyroid hormones thyroxine (T4) and triiodothyronine (T3), regulating metabolic rate, cellular respiration, and fetal neurodevelopment. Adult RDA is 150 µg, with an Upper Limit of 1,100 µg/day.

View full Iodine (Elemental I) spec sheet →

Vitamin K1 is a fat-soluble naphthoquinone synthesized by photosynthetic plants. Adequate Intake (AI) is 120µg (men) / 90µg (women), acting as an essential cofactor for gamma-glutamyl carboxylase in blood clotting and osteocalcin bone mineralization.

View full Vitamin K1 (Phylloquinone) spec sheet →

Specification Comparison Table

10 Parameters
Parameter / Spec
Nutrient Type
Essential Trace Halogen Element Fat-Soluble Naphthoquinone Vitamin
Tolerable Upper Limit (UL)
1,100 µg / day (Avoid Wolff-Chaikoff thyroid autoregulatory shutdown) None Established (No adverse effects reported)
Chemical Forms
Iodide (I- / Potassium Iodide KI, Potassium Iodate KIO3 in iodized salt), Molecular Iodine Phylloquinone (K1 - Green Plants), Menaquinones (K2: MK-4, MK-7 - Ferments/Animal)
Primary Biological Function
Constituent of Thyroxine (T4, 4 iodine atoms / 65% by weight) and Triiodothyronine (T3, 3 iodine atoms / 59% by weight) Gamma-glutamyl carboxylase cofactor (Factors II, VII, IX, X), Osteocalcin carboxylation, Matrix Gla Protein (MGP) vascular calcification inhibitor
Deficiency Condition
Endemic Goiter (Compensatory thyroid enlargement), Congenital Hypothyroidism / Cretinism (Permanent neurodevelopmental impairment), Maternal miscarriages Coagulopathy, Hemorrhage, Impaired bone density
Top Whole Food Sources
Kombu Kelp, Nori Seaweed, Atlantic Cod, Eastern Oysters, Iodized Table Salt, Greek Yogurt, Dairy Milk, Eggs Spinach, Kale, Broccoli, Brussels Sprouts, Natto (K2 MK-7), Parsley
Adult RDA / RDI
150 µg / day (220 µg pregnancy / 290 µg lactation)
Iodized Salt Public Health Impact
Universal salt iodization (45–75 mg KI / kg salt) is hailed as one of the greatest global public health achievements, eradicating cretinism worldwide
Adult Adequate Intake (AI)
120 µg / day (Men) / 90 µg / day (Women)
Warfarin / Anticoagulant Interaction
Direct competitive antagonist to Coumadin/Warfarin (requires consistent daily intake)