# item.guide
Side-by-Side Comparison Essential Vitamins & Minerals

Vitamin B5 (Pantothenic Acid) vs. Vitamin K1 (Phylloquinone)

Comparing 2 standards across 9 specifications. 9 key differences identified.

Comparing:
Vitamin B5 (Pantothenic Acid)
Vitamin K1 (Phylloquinone)

Vitamin B5 is an essential water-soluble vitamin required for the synthesis of Coenzyme A (CoA) and acyl carrier protein (ACP), vital in fatty acid synthesis and beta-oxidation. Adequate Intake (AI) is 5.0 mg/day (no Upper Limit established).

View full Vitamin B5 (Pantothenic Acid) spec sheet →

Vitamin K1 is a fat-soluble naphthoquinone synthesized by photosynthetic plants. Adequate Intake (AI) is 120µg (men) / 90µg (women), acting as an essential cofactor for gamma-glutamyl carboxylase in blood clotting and osteocalcin bone mineralization.

View full Vitamin K1 (Phylloquinone) spec sheet →

Specification Comparison Table

9 Parameters
Parameter / Spec
Nutrient Type
Water-Soluble Amide Vitamin Fat-Soluble Naphthoquinone Vitamin
Adult Adequate Intake (AI)
5.0 mg / day (6.0mg pregnancy, 7.0mg lactation) 120 µg / day (Men) / 90 µg / day (Women)
Tolerable Upper Limit (UL)
None Established (Extremely low toxicity) None Established (No adverse effects reported)
Chemical Forms
D-Pantothenic Acid, Calcium Pantothenate (Stable synthetic), Pantethine (Active dimer) Phylloquinone (K1 - Green Plants), Menaquinones (K2: MK-4, MK-7 - Ferments/Animal)
Primary Biological Function
Coenzyme A (CoA) backbone (Acetyl-CoA, Succinyl-CoA), Acyl Carrier Protein in fatty acid synthase, Steroid hormone synthesis Gamma-glutamyl carboxylase cofactor (Factors II, VII, IX, X), Osteocalcin carboxylation, Matrix Gla Protein (MGP) vascular calcification inhibitor
Deficiency Condition
Extremely rare ('Pantothen' = everywhere in foods); 'Burning Feet' syndrome (paresthesia), fatigue Coagulopathy, Hemorrhage, Impaired bone density
Top Whole Food Sources
Shiitake Mushrooms, Beef Liver, Chicken Liver, Sunflower Seeds, Egg Yolk, Hass Avocado, Whole Milk Spinach, Kale, Broccoli, Brussels Sprouts, Natto (K2 MK-7), Parsley
Thermal Processing Losses
20–50% lost during meat canning, boiling, and flour milling refining
Warfarin / Anticoagulant Interaction
Direct competitive antagonist to Coumadin/Warfarin (requires consistent daily intake)