Vitamin B5 (Pantothenic Acid) vs. Vitamin B7 (Biotin / Vitamin H)
Comparing 2 standards across 9 specifications. 9 key differences identified.
Vitamin B5 is an essential water-soluble vitamin required for the synthesis of Coenzyme A (CoA) and acyl carrier protein (ACP), vital in fatty acid synthesis and beta-oxidation. Adequate Intake (AI) is 5.0 mg/day (no Upper Limit established).
Vitamin B7 is an essential sulfur-containing water-soluble vitamin serving as a prosthetic group for five carboxylase enzymes in gluconeogenesis, lipogenesis, and branched-chain amino acid catabolism. Adequate Intake (AI) is 30 µg/day (no Upper Limit established).
Specification Comparison Table
9 Parameters| Parameter / Spec | ||
|---|---|---|
|
Nutrient Type
|
Water-Soluble Amide Vitamin | Water-Soluble Ureido-Tetrahydrothiophene Vitamin |
|
Adult Adequate Intake (AI)
|
5.0 mg / day (6.0mg pregnancy, 7.0mg lactation) | 30 µg / day (35 µg during lactation) |
|
Tolerable Upper Limit (UL)
|
None Established (Extremely low toxicity) | None Established (No adverse effects recorded) |
|
Chemical Forms
|
D-Pantothenic Acid, Calcium Pantothenate (Stable synthetic), Pantethine (Active dimer) | D-Biotin (Biologically active isomer), Biocytin (Biotinyl-lysine) |
|
Primary Biological Function
|
Coenzyme A (CoA) backbone (Acetyl-CoA, Succinyl-CoA), Acyl Carrier Protein in fatty acid synthase, Steroid hormone synthesis | Prosthetic group for Pyruvate Carboxylase (Gluconeogenesis), Acetyl-CoA Carboxylase (Fatty acid synthesis), Propionyl-CoA Carboxylase, Histone biotinylation |
|
Deficiency Condition
|
Extremely rare ('Pantothen' = everywhere in foods); 'Burning Feet' syndrome (paresthesia), fatigue | Alopecia (Hair loss), Erythematous scaly periorofacial rash, Brittle nails, Neurological depression / hallucinations |
|
Top Whole Food Sources
|
Shiitake Mushrooms, Beef Liver, Chicken Liver, Sunflower Seeds, Egg Yolk, Hass Avocado, Whole Milk | Egg Yolk, Beef Liver, Salmon, Pork Chop, Sunflower Seeds, Almonds, Sweet Potatoes |
|
Thermal Processing Losses
|
20–50% lost during meat canning, boiling, and flour milling refining | — |
|
Raw Egg White (Avidin) Interaction
|
— | Raw egg albumen contains avidin glycoprotein which binds biotin with Kd ~10^-15 M (the strongest non-covalent bond known), completely blocking absorption unless cooked |