# item.guide
Side-by-Side Comparison Essential Vitamins & Minerals

Vitamin B5 (Pantothenic Acid) vs. Vitamin B7 (Biotin / Vitamin H)

Comparing 2 standards across 9 specifications. 9 key differences identified.

Comparing:
Vitamin B5 (Pantothenic Acid)
Vitamin B7 (Biotin / Vitamin H)

Vitamin B5 is an essential water-soluble vitamin required for the synthesis of Coenzyme A (CoA) and acyl carrier protein (ACP), vital in fatty acid synthesis and beta-oxidation. Adequate Intake (AI) is 5.0 mg/day (no Upper Limit established).

View full Vitamin B5 (Pantothenic Acid) spec sheet →

Vitamin B7 is an essential sulfur-containing water-soluble vitamin serving as a prosthetic group for five carboxylase enzymes in gluconeogenesis, lipogenesis, and branched-chain amino acid catabolism. Adequate Intake (AI) is 30 µg/day (no Upper Limit established).

View full Vitamin B7 (Biotin / Vitamin H) spec sheet →

Specification Comparison Table

9 Parameters
Parameter / Spec
Nutrient Type
Water-Soluble Amide Vitamin Water-Soluble Ureido-Tetrahydrothiophene Vitamin
Adult Adequate Intake (AI)
5.0 mg / day (6.0mg pregnancy, 7.0mg lactation) 30 µg / day (35 µg during lactation)
Tolerable Upper Limit (UL)
None Established (Extremely low toxicity) None Established (No adverse effects recorded)
Chemical Forms
D-Pantothenic Acid, Calcium Pantothenate (Stable synthetic), Pantethine (Active dimer) D-Biotin (Biologically active isomer), Biocytin (Biotinyl-lysine)
Primary Biological Function
Coenzyme A (CoA) backbone (Acetyl-CoA, Succinyl-CoA), Acyl Carrier Protein in fatty acid synthase, Steroid hormone synthesis Prosthetic group for Pyruvate Carboxylase (Gluconeogenesis), Acetyl-CoA Carboxylase (Fatty acid synthesis), Propionyl-CoA Carboxylase, Histone biotinylation
Deficiency Condition
Extremely rare ('Pantothen' = everywhere in foods); 'Burning Feet' syndrome (paresthesia), fatigue Alopecia (Hair loss), Erythematous scaly periorofacial rash, Brittle nails, Neurological depression / hallucinations
Top Whole Food Sources
Shiitake Mushrooms, Beef Liver, Chicken Liver, Sunflower Seeds, Egg Yolk, Hass Avocado, Whole Milk Egg Yolk, Beef Liver, Salmon, Pork Chop, Sunflower Seeds, Almonds, Sweet Potatoes
Thermal Processing Losses
20–50% lost during meat canning, boiling, and flour milling refining
Raw Egg White (Avidin) Interaction
Raw egg albumen contains avidin glycoprotein which binds biotin with Kd ~10^-15 M (the strongest non-covalent bond known), completely blocking absorption unless cooked