# item.guide
Side-by-Side Comparison Essential Vitamins & Minerals

Vitamin B7 (Biotin / Vitamin H) vs. Vitamin K1 (Phylloquinone)

Comparing 2 standards across 9 specifications. 9 key differences identified.

Comparing:
Vitamin B7 (Biotin / Vitamin H)
Vitamin K1 (Phylloquinone)
Vitamin B7 (Biotin / Vitamin H) →

Vitamin B7 is an essential sulfur-containing water-soluble vitamin serving as a prosthetic group for five carboxylase enzymes in gluconeogenesis, lipogenesis, and branched-chain amino acid catabolism. Adequate Intake (AI) is 30 µg/day (no Upper Limit established).

View full Vitamin B7 (Biotin / Vitamin H) spec sheet →
Vitamin K1 (Phylloquinone) →

Vitamin K1 is a fat-soluble naphthoquinone synthesized by photosynthetic plants. Adequate Intake (AI) is 120µg (men) / 90µg (women), acting as an essential cofactor for gamma-glutamyl carboxylase in blood clotting and osteocalcin bone mineralization.

View full Vitamin K1 (Phylloquinone) spec sheet →

Specification Comparison Table

9 Parameters
Parameter / Spec
Vitamin B7 (Biotin / Vitamin H)
Vitamin K1 (Phylloquinone)
Nutrient Type
Water-Soluble Ureido-Tetrahydrothiophene Vitamin Fat-Soluble Naphthoquinone Vitamin
Adult Adequate Intake (AI)
30 µg / day (35 µg during lactation) 120 µg / day (Men) / 90 µg / day (Women)
Tolerable Upper Limit (UL)
None Established (No adverse effects recorded) None Established (No adverse effects reported)
Chemical Forms
D-Biotin (Biologically active isomer), Biocytin (Biotinyl-lysine) Phylloquinone (K1 - Green Plants), Menaquinones (K2: MK-4, MK-7 - Ferments/Animal)
Primary Biological Function
Prosthetic group for Pyruvate Carboxylase (Gluconeogenesis), Acetyl-CoA Carboxylase (Fatty acid synthesis), Propionyl-CoA Carboxylase, Histone biotinylation Gamma-glutamyl carboxylase cofactor (Factors II, VII, IX, X), Osteocalcin carboxylation, Matrix Gla Protein (MGP) vascular calcification inhibitor
Deficiency Condition
Alopecia (Hair loss), Erythematous scaly periorofacial rash, Brittle nails, Neurological depression / hallucinations Coagulopathy, Hemorrhage, Impaired bone density
Top Whole Food Sources
Egg Yolk, Beef Liver, Salmon, Pork Chop, Sunflower Seeds, Almonds, Sweet Potatoes Spinach, Kale, Broccoli, Brussels Sprouts, Natto (K2 MK-7), Parsley
Raw Egg White (Avidin) Interaction
Raw egg albumen contains avidin glycoprotein which binds biotin with Kd ~10^-15 M (the strongest non-covalent bond known), completely blocking absorption unless cooked —
Warfarin / Anticoagulant Interaction
— Direct competitive antagonist to Coumadin/Warfarin (requires consistent daily intake)

Other Alternatives to Compare

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