E627: Disodium Guanylate (GMP Umami Synergist) vs. E968: Erythritol (Zero-Calorie Fermented Polyol)
Comparing 2 standards across 12 specifications. 12 key differences identified.
E627 (Disodium 5'-Guanylate / GMP) is the sodium salt of guanylic acid, a purine nucleotide naturally concentrated in dried shiitake mushrooms. INS 627, ADI is Not Specified, exhibiting massive 8x–30x synergistic umami amplification when paired with MSG.
E968 (Erythritol) is a four-carbon polyol produced by microbial fermentation of glucose by Moniliella pollinis. INS 968, ADI is Not Specified, delivering 70% the sweetness of sucrose with 0.0–0.2 kcal/g, zero GI, and 90% urinary excretion avoiding digestive distress.
Specification Comparison Table
12 Parameters| Parameter / Spec | ||
|---|---|---|
|
E-Number Code
|
E627 | E968 |
|
INS / Codex Number
|
INS 627 | INS 968 |
|
Functional Class
|
Flavor Enhancer (Purine Nucleotide Umami Synergist) | Non-Nutritive Bulk Sweetener, Flavor Enhancer, Humectant |
|
Acceptable Daily Intake (ADI)
|
Not Specified (Quantum Satis) | Not Specified (Highest digestive tolerance among all polyols: 0.66–0.80 g/kg bw) |
|
Common Target Foods
|
Savory snack seasonings (Doritos, chips), instant ramen noodle seasoning packets, bouillon cubes | Keto baked goods, monk fruit/stevia blends (Swerve), zero-sugar confectionery |
|
Dietary Compliance
|
Vegan (Microbial fermentation of tapioca/sugar), Halal, Kosher | 100% Vegan (Yeast fermentation of corn glucose), Halal, Kosher, Non-GMO |
|
Safety Approval
|
EFSA Authorized / FDA GRAS (21 CFR 172.530) | EFSA Authorized / FDA GRAS (GRN 76) |
|
Chemical Formula
|
C10H12N5Na2O8P · xH2O | — |
|
Primary Mechanism
|
Binds allosteric site on T1R1/T1R3 umami receptor, locking glutamate into the orthosteric binding pocket | — |
|
Relative Sweetness Index
|
— | 70% Sucrose |
|
Caloric Value
|
— | 0.2 kcal / g (Legal EU/US: 0.0 kcal / g) kcal/g |
|
Glycemic Index (GI)
|
— | 0 (Zero effect on blood glucose or insulin levels) |