E627: Disodium Guanylate (GMP Umami Synergist) vs. E960: Steviol Glycosides (Reb-A / Stevia Extract)
Comparing 2 standards across 12 specifications. 12 key differences identified.
E627 (Disodium 5'-Guanylate / GMP) is the sodium salt of guanylic acid, a purine nucleotide naturally concentrated in dried shiitake mushrooms. INS 627, ADI is Not Specified, exhibiting massive 8x–30x synergistic umami amplification when paired with MSG.
E960 (Steviol Glycosides / Rebaudioside A) is a natural zero-calorie sweetener water-extracted from the leaves of the Stevia plant (Stevia rebaudiana). INS 960a, ADI is 4 mg/kg bw/day (as steviol equivalents), providing 250–350x sucrose sweetness.
Specification Comparison Table
12 Parameters| Parameter / Spec | ||
|---|---|---|
|
E-Number Code
|
E627 | E960 |
|
INS / Codex Number
|
INS 627 | INS 960a / 960c |
|
Functional Class
|
Flavor Enhancer (Purine Nucleotide Umami Synergist) | Natural High-Intensity Sweetener |
|
Acceptable Daily Intake (ADI)
|
Not Specified (Quantum Satis) | 4 mg / kg body weight per day (as steviol equivalents) |
|
Common Target Foods
|
Savory snack seasonings (Doritos, chips), instant ramen noodle seasoning packets, bouillon cubes | Natural zero-calorie sodas (Zevia), flavored yogurts, protein shakes, tabletop drops |
|
Dietary Compliance
|
Vegan (Microbial fermentation of tapioca/sugar), Halal, Kosher | 100% Vegan (Stevia leaf water extraction), Halal, Kosher, Non-GMO |
|
Safety Approval
|
EFSA Authorized / FDA GRAS (21 CFR 172.530) | EFSA Authorized / FDA GRAS Notices (GRN 252) |
|
Chemical Formula
|
C10H12N5Na2O8P · xH2O | — |
|
Primary Mechanism
|
Binds allosteric site on T1R1/T1R3 umami receptor, locking glutamate into the orthosteric binding pocket | — |
|
Relative Sweetness Index
|
— | 250 – 350x Sucrose (Reb-A >98%) |
|
Caloric Value
|
— | 0.0 kcal / g kcal/g |
|
Glycemic Index (GI)
|
— | 0 (Zero effect on blood glucose or insulin) |