E627: Disodium Guanylate (GMP Umami Synergist) vs. E950: Acesulfame Potassium (Ace-K / 200x Sweetener)
Comparing 2 standards across 11 specifications. 11 key differences identified.
E627 (Disodium 5'-Guanylate / GMP) is the sodium salt of guanylic acid, a purine nucleotide naturally concentrated in dried shiitake mushrooms. INS 627, ADI is Not Specified, exhibiting massive 8x–30x synergistic umami amplification when paired with MSG.
E950 (Acesulfame K / Ace-K) is a calorie-free, heat-stable synthetic potassium salt sweetener approximately 200 times sweeter than sucrose. INS 950, ADI is 9 mg/kg bw/day, famous for blending with sucralose and aspartame to produce sugar-identical taste curves.
Specification Comparison Table
11 Parameters| Parameter / Spec | ||
|---|---|---|
|
E-Number Code
|
E627 | E950 |
|
INS / Codex Number
|
INS 627 | INS 950 |
|
Functional Class
|
Flavor Enhancer (Purine Nucleotide Umami Synergist) | Non-Nutritive High-Intensity Sweetener |
|
Acceptable Daily Intake (ADI)
|
Not Specified (Quantum Satis) | 9 mg / kg body weight per day |
|
Primary Mechanism
|
Binds allosteric site on T1R1/T1R3 umami receptor, locking glutamate into the orthosteric binding pocket | High-affinity agonist for T1R2 + T1R3 sweet taste receptor dimer |
|
Common Target Foods
|
Savory snack seasonings (Doritos, chips), instant ramen noodle seasoning packets, bouillon cubes | Diet sodas (Coke Zero), sugar-free energy drinks, baked goods, sugar-free chewing gum |
|
Dietary Compliance
|
Vegan (Microbial fermentation of tapioca/sugar), Halal, Kosher | 100% Vegan, Halal, Kosher, Diabetic Safe, Dental Safe (Non-cariogenic) |
|
Safety Approval
|
EFSA Authorized / FDA GRAS (21 CFR 172.530) | EFSA Authorized / FDA Approved (21 CFR 172.800) |
|
Chemical Formula
|
C10H12N5Na2O8P · xH2O | — |
|
Relative Sweetness Index
|
— | 200x Sucrose |
|
Caloric Value
|
— | 0.0 kcal / g (Excreted unchanged by kidneys) kcal/g |