Side-by-Side Comparison
Food Additives & E-Numbers
E306: Tocopherol-Rich Extract (Natural Vitamin E Antioxidant) vs. E627: Disodium Guanylate (GMP Umami Synergist)
Comparing 2 standards across 10 specifications. 10 key differences identified.
Comparing:
E306: Tocopherol-Rich Extract (Natural Vitamin E Antioxidant)
E627: Disodium Guanylate (GMP Umami Synergist)
E306 is a natural mixture of alpha-, beta-, gamma-, and delta-tocopherols steam-distilled from vegetable oils (soybean, sunflower). INS 306, ADI is Not Limited, serving as the gold standard lipid-soluble antioxidant in fats and oils.
E627 (Disodium 5'-Guanylate / GMP) is the sodium salt of guanylic acid, a purine nucleotide naturally concentrated in dried shiitake mushrooms. INS 627, ADI is Not Specified, exhibiting massive 8x–30x synergistic umami amplification when paired with MSG.
Specification Comparison Table
10 Parameters| Parameter / Spec | ||
|---|---|---|
|
E-Number Code
|
E306 | E627 |
|
INS / Codex Number
|
INS 306 | INS 627 |
|
Functional Class
|
Antioxidant (Lipid Peroxidation Inhibitor) | Flavor Enhancer (Purine Nucleotide Umami Synergist) |
|
Acceptable Daily Intake (ADI)
|
Not Limited (Quantum Satis) | Not Specified (Quantum Satis) |
|
Primary Mechanism
|
Free-radical scavenger donating phenolic hydrogen atoms to peroxyl radicals (ROO•), breaking lipid auto-oxidation chain | Binds allosteric site on T1R1/T1R3 umami receptor, locking glutamate into the orthosteric binding pocket |
|
Common Target Foods
|
Vegetable cooking oils, margarines, infant formula, fish oil capsules, potato crisps | Savory snack seasonings (Doritos, chips), instant ramen noodle seasoning packets, bouillon cubes |
|
Dietary Compliance
|
100% Vegan (Plant oil distillate), Halal, Kosher Certified | Vegan (Microbial fermentation of tapioca/sugar), Halal, Kosher |
|
Safety Approval
|
EFSA Authorized / FDA GRAS (21 CFR 184.1890) | EFSA Authorized / FDA GRAS (21 CFR 172.530) |
|
Active Isomers
|
d-Gamma-Tocopherol, d-Delta-Tocopherol, d-Alpha-Tocopherol | — |
|
Chemical Formula
|
— | C10H12N5Na2O8P · xH2O |
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