# item.guide
Side-by-Side Comparison Essential Vitamins & Minerals

Calcium (Elemental Ca) vs. Vitamin E (d-Alpha-Tocopherol)

Comparing 2 standards across 9 specifications. 9 key differences identified.

Comparing:
Calcium (Elemental Ca)
Vitamin E (d-Alpha-Tocopherol)

Calcium is the most abundant mineral in the human body (1.0–1.2 kg), with 99% sequestered in hydroxyapatite bone lattice and 1% tightly regulated at 8.5–10.5 mg/dL serum for cardiac contractility, nerve signaling, and blood coagulation. Adult RDA is 1,000–1,200 mg/day.

View full Calcium (Elemental Ca) spec sheet →

Vitamin E is the principal fat-soluble peroxyl radical-scavenging antioxidant protecting cellular polyunsaturated membrane phospholipids. Adult RDA is 15 mg (22.4 IU) of d-alpha-tocopherol, with a Tolerable Upper Limit of 1,000 mg (1,500 IU)/day.

View full Vitamin E (d-Alpha-Tocopherol) spec sheet →

Specification Comparison Table

9 Parameters
Parameter / Spec
Nutrient Type
Essential Macromineral Fat-Soluble Chromanol Lipophilic Vitamin
Adult RDA / RDI
1,000 mg / day (Men 19–70, Women 19–50) / 1,200 mg (Women 51+, Men 71+) 15 mg / day (22.4 IU) of 2R-alpha-tocopherol
Tolerable Upper Limit (UL)
2,500 mg / day (Adults 19–50) / 2,000 mg / day (Adults 51+) (Avoid nephrolithiasis / vascular calcification) 1,000 mg / day (1,500 IU synthetic) (Excess impairs Vitamin K clotting cascade)
Chemical Forms
Calcium Carbonate (40% elemental Ca / requires stomach acid), Calcium Citrate (21% elemental Ca / acid-independent), Hydroxyapatite RRR-alpha-Tocopherol (Natural d-alpha), all-rac-alpha-Tocopherol (Synthetic dl-alpha), Gamma/Delta-Tocopherols
Primary Biological Function
Hydroxyapatite bone/dental structure [Ca10(PO4)6(OH)2], Troponin-C actin-myosin muscle contraction, Factor IV blood clotting cascade, Exocytosis neurotransmitter release Breaks lipid peroxidation chain in PUFA cell membranes, protects LDL from oxidative modification, maintains erythrocyte membrane integrity
Deficiency Condition
Osteoporosis, Osteopenia, Rickets (children), Tetany (Trousseau's and Chvostek's signs of hypocalcemia) Hemolytic anemia, Spinocerebellar ataxia, Peripheral neuropathy, Loss of vibratory/proprioceptive sense
Top Whole Food Sources
Parmigiano-Reggiano, Sharp Cheddar, Whole Milk, Sardines with bones, Kale, Tofu (Calcium-set), Fortified Plant Milk Wheat Germ Oil, Sunflower Seeds, Raw Almonds, Hazelnuts, Sunflower Oil, Spinach, Hass Avocado
Parathyroid Hormone (PTH) Homeostasis
Serum Ca2+ drop triggers PTH secretion, stimulating renal 1-alpha-hydroxylase to produce active Calcitriol (1,25-OH-D3) and osteoclast bone resorption
Hepatic Alpha-TTP Specificity
The liver secretes only alpha-tocopherol into VLDL via Alpha-Tocopherol Transfer Protein (alpha-TTP); other tocopherols are degraded in bile