# item.guide
Side-by-Side Comparison Essential Vitamins & Minerals

Calcium (Elemental Ca) vs. Iron (Heme & Non-Heme)

Comparing 2 standards across 9 specifications. 9 key differences identified.

Comparing:
Calcium (Elemental Ca)
Iron (Heme & Non-Heme)

Calcium is the most abundant mineral in the human body (1.0–1.2 kg), with 99% sequestered in hydroxyapatite bone lattice and 1% tightly regulated at 8.5–10.5 mg/dL serum for cardiac contractility, nerve signaling, and blood coagulation. Adult RDA is 1,000–1,200 mg/day.

View full Calcium (Elemental Ca) spec sheet →

Iron is an essential redox trace element central to hemoglobin oxygen transport, myoglobin storage, and mitochondrial electron transport chain cytochromes. Adult RDA is 8mg (men/post-menopausal women) / 18mg (pre-menopausal women), with a Tolerable Upper Limit of 45mg/day.

View full Iron (Heme & Non-Heme) spec sheet →

Specification Comparison Table

9 Parameters
Parameter / Spec
Nutrient Type
Essential Macromineral Essential Trace Mineral
Adult RDA / RDI
1,000 mg / day (Men 19–70, Women 19–50) / 1,200 mg (Women 51+, Men 71+) 8 mg (Men) / 18 mg (Women 19–50) / 27 mg (Pregnancy)
Tolerable Upper Limit (UL)
2,500 mg / day (Adults 19–50) / 2,000 mg / day (Adults 51+) (Avoid nephrolithiasis / vascular calcification) 45 mg / day (Hemochromatosis / Fenton reaction oxidative stress)
Chemical Forms
Calcium Carbonate (40% elemental Ca / requires stomach acid), Calcium Citrate (21% elemental Ca / acid-independent), Hydroxyapatite Heme Iron (Fe2+ Porphyrin - Animal), Non-Heme Iron (Fe3+ Ferric / Fe2+ Ferrous - Plants/Supplements)
Primary Biological Function
Hydroxyapatite bone/dental structure [Ca10(PO4)6(OH)2], Troponin-C actin-myosin muscle contraction, Factor IV blood clotting cascade, Exocytosis neurotransmitter release Hemoglobin O2 transport, Myoglobin O2 storage, Cytochrome c electron transport, Catalase
Deficiency Condition
Osteoporosis, Osteopenia, Rickets (children), Tetany (Trousseau's and Chvostek's signs of hypocalcemia) Microcytic Hypochromic Anemia, Severe fatigue, Restless legs syndrome, Pica
Top Whole Food Sources
Parmigiano-Reggiano, Sharp Cheddar, Whole Milk, Sardines with bones, Kale, Tofu (Calcium-set), Fortified Plant Milk Beef Liver, Oysters, Duck Breast, Beef Ribeye, Lentils, Spinach, Dark Chocolate
Parathyroid Hormone (PTH) Homeostasis
Serum Ca2+ drop triggers PTH secretion, stimulating renal 1-alpha-hydroxylase to produce active Calcitriol (1,25-OH-D3) and osteoclast bone resorption
Bioavailability Difference
Heme: 15–35% absorption (uninhibited); Non-Heme: 2–20% (inhibited by phytates/calcium, boosted by Vitamin C)