# item.guide
Side-by-Side Comparison Essential Vitamins & Minerals

Calcium (Elemental Ca) vs. Iodine (Elemental I)

Comparing 2 standards across 9 specifications. 9 key differences identified.

Comparing:
Calcium (Elemental Ca)
Iodine (Elemental I)

Calcium is the most abundant mineral in the human body (1.0–1.2 kg), with 99% sequestered in hydroxyapatite bone lattice and 1% tightly regulated at 8.5–10.5 mg/dL serum for cardiac contractility, nerve signaling, and blood coagulation. Adult RDA is 1,000–1,200 mg/day.

View full Calcium (Elemental Ca) spec sheet →

Iodine is an essential halogen trace element required exclusively as an essential structural component of thyroid hormones thyroxine (T4) and triiodothyronine (T3), regulating metabolic rate, cellular respiration, and fetal neurodevelopment. Adult RDA is 150 µg, with an Upper Limit of 1,100 µg/day.

View full Iodine (Elemental I) spec sheet →

Specification Comparison Table

9 Parameters
Parameter / Spec
Nutrient Type
Essential Macromineral Essential Trace Halogen Element
Adult RDA / RDI
1,000 mg / day (Men 19–70, Women 19–50) / 1,200 mg (Women 51+, Men 71+) 150 µg / day (220 µg pregnancy / 290 µg lactation)
Tolerable Upper Limit (UL)
2,500 mg / day (Adults 19–50) / 2,000 mg / day (Adults 51+) (Avoid nephrolithiasis / vascular calcification) 1,100 µg / day (Avoid Wolff-Chaikoff thyroid autoregulatory shutdown)
Chemical Forms
Calcium Carbonate (40% elemental Ca / requires stomach acid), Calcium Citrate (21% elemental Ca / acid-independent), Hydroxyapatite Iodide (I- / Potassium Iodide KI, Potassium Iodate KIO3 in iodized salt), Molecular Iodine
Primary Biological Function
Hydroxyapatite bone/dental structure [Ca10(PO4)6(OH)2], Troponin-C actin-myosin muscle contraction, Factor IV blood clotting cascade, Exocytosis neurotransmitter release Constituent of Thyroxine (T4, 4 iodine atoms / 65% by weight) and Triiodothyronine (T3, 3 iodine atoms / 59% by weight)
Deficiency Condition
Osteoporosis, Osteopenia, Rickets (children), Tetany (Trousseau's and Chvostek's signs of hypocalcemia) Endemic Goiter (Compensatory thyroid enlargement), Congenital Hypothyroidism / Cretinism (Permanent neurodevelopmental impairment), Maternal miscarriages
Top Whole Food Sources
Parmigiano-Reggiano, Sharp Cheddar, Whole Milk, Sardines with bones, Kale, Tofu (Calcium-set), Fortified Plant Milk Kombu Kelp, Nori Seaweed, Atlantic Cod, Eastern Oysters, Iodized Table Salt, Greek Yogurt, Dairy Milk, Eggs
Parathyroid Hormone (PTH) Homeostasis
Serum Ca2+ drop triggers PTH secretion, stimulating renal 1-alpha-hydroxylase to produce active Calcitriol (1,25-OH-D3) and osteoclast bone resorption
Iodized Salt Public Health Impact
Universal salt iodization (45–75 mg KI / kg salt) is hailed as one of the greatest global public health achievements, eradicating cretinism worldwide