E460: Microcrystalline Cellulose (MCC / Dietary Bulking) vs. E627: Disodium Guanylate (GMP Umami Synergist)
Comparing 2 standards across 9 specifications. 9 key differences identified.
E460 (Microcrystalline Cellulose / MCC) is purified, depolymerized wood pulp cellulose prepared by acid hydrolysis. INS 460(i), ADI is Not Limited (Quantum Satis), functioning as a zero-calorie bulking agent, anti-caking agent, and fat mimetic in low-calorie foods.
E627 (Disodium 5'-Guanylate / GMP) is the sodium salt of guanylic acid, a purine nucleotide naturally concentrated in dried shiitake mushrooms. INS 627, ADI is Not Specified, exhibiting massive 8x–30x synergistic umami amplification when paired with MSG.
Specification Comparison Table
9 Parameters| Parameter / Spec | ||
|---|---|---|
|
E-Number Code
|
E460 | E627 |
|
INS / Codex Number
|
INS 460(i) | INS 627 |
|
Functional Class
|
Bulking Agent, Anti-Caking Agent, Stabilizer, Fat Replacer | Flavor Enhancer (Purine Nucleotide Umami Synergist) |
|
Acceptable Daily Intake (ADI)
|
Not Limited (Quantum Satis) | Not Specified (Quantum Satis) |
|
Chemical Formula
|
(C6H10O5)n (Insoluble linear beta-1,4-glucan polymer) | C10H12N5Na2O8P · xH2O |
|
Primary Mechanism
|
Crystalline cellulose micro-particles mimic creamy lipid mouthfeel without calories; prevents powder agglomeration | Binds allosteric site on T1R1/T1R3 umami receptor, locking glutamate into the orthosteric binding pocket |
|
Common Target Foods
|
Shredded cheeses (Prevents clumping), low-fat dressings, dietary supplement tablets, diet foods | Savory snack seasonings (Doritos, chips), instant ramen noodle seasoning packets, bouillon cubes |
|
Dietary Compliance
|
100% Vegan (Plant wood pulp), Halal, Kosher, Gluten-Free | Vegan (Microbial fermentation of tapioca/sugar), Halal, Kosher |
|
Safety Approval
|
EFSA Authorized / FDA GRAS (21 CFR 184.1323) | EFSA Authorized / FDA GRAS (21 CFR 172.530) |