# item.guide
Side-by-Side Comparison Food Additives & E-Numbers

E422: Glycerol (Glycerin Humectant & Solvent) vs. E635: Disodium 5'-Ribonucleotides (I+G Blend)

Comparing 2 standards across 10 specifications. 10 key differences identified.

Comparing:
E422: Glycerol (Glycerin Humectant & Solvent)
E635: Disodium 5'-Ribonucleotides (I+G Blend)

E422 (Glycerol / Glycerin) is a sweet, viscous trihydroxy alcohol (polyol) obtained via lipid hydrolysis. INS 422, ADI is Not Limited (Quantum Satis), acting as an essential humectant, moisture retainer, and freeze-point depressant in baked goods and icings.

View full E422: Glycerol (Glycerin Humectant & Solvent) spec sheet →

E635 (I+G) is a standardized 50/50 co-crystallized blend of disodium inosinate (E631) and disodium guanylate (E627). INS 635, ADI is Not Specified, serving as the commercial standard umami booster in global food manufacturing.

View full E635: Disodium 5'-Ribonucleotides (I+G Blend) spec sheet →

Specification Comparison Table

10 Parameters
Parameter / Spec
E-Number Code
E422 E635
INS / Codex Number
INS 422 INS 635
Functional Class
Humectant, Solvent, Sweetener, Bodying Agent Flavor Enhancer (Standard 50/50 IMP + GMP Umami Blend)
Acceptable Daily Intake (ADI)
Not Limited (Quantum Satis) Not Specified (Quantum Satis)
Primary Mechanism
Strongly hygroscopic triol binds water molecules, lowering water activity (aw) and preventing staling Maximum simultaneous allosteric sensitization of oral T1R1+T1R3 umami receptor sites
Common Target Foods
Fondant icings, soft-baked cookies, energy bars, cake sponges, liqueur bodying Flavored potato chips, instant noodles, dry soup mixes, processed meats, barbecue sauces
Dietary Compliance
Vegan (When derived from plant fats), Halal, Kosher Vegan (Bacterial sugar fermentation), Halal, Kosher
Safety Approval
EFSA Authorized / FDA GRAS (21 CFR 184.1320) EFSA Authorized / FDA GRAS
Chemical Formula
C3H8O3 (Propane-1,2,3-triol)
Composition
50% Disodium Inosinate (E631) + 50% Disodium Guanylate (E627)

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Humectant & Solvent) vs. E406: Agar-Agar (Seaweed Hydrocolloid Gel) → Compare E422: Glycerol (Glycerin Humectant & Solvent) vs. E407: Carrageenan (Dairy Stabilizer Hydrocolloid) → Compare E422: Glycerol (Glycerin Humectant & Solvent) vs. E410: Locust Bean Gum (Carob Bean Gum / LBG) → Compare E422: Glycerol (Glycerin Humectant & Solvent) vs. E412: Guar Gum (Cold-Soluble Galactomannan) → Compare E422: Glycerol (Glycerin Humectant & Solvent) vs. E414: Gum Arabic (Acacia Gum Emulsifier) → Compare E422: Glycerol (Glycerin Humectant & Solvent) vs. E415: Xanthan Gum (Pseudoplastic Hydrocolloid Thickener) → Compare E422: Glycerol (Glycerin Humectant & Solvent) vs. E440: Pectin (Citrus & Apple Jam Gelling Fiber) → Compare E422: Glycerol (Glycerin Humectant & Solvent) vs. E460: Microcrystalline Cellulose (MCC / Dietary Bulking) → Compare E422: Glycerol (Glycerin Humectant & Solvent) vs. E471: Mono- & Diglycerides of Fatty Acids (Bread Softener) → Compare E422: Glycerol (Glycerin Humectant & 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