E635: Disodium 5'-Ribonucleotides (I+G Blend)

Direct Answer

E635 (I+G) is a standardized 50/50 co-crystallized blend of disodium inosinate (E631) and disodium guanylate (E627). INS 635, ADI is Not Specified, serving as the commercial standard umami booster in global food manufacturing.

Source: Codex Alimentarius / EFSA · Last reviewed Aug 28, 2026

Specs

E-Number Code	E635
INS / Codex Number	INS 635
Functional Class	Flavor Enhancer (Standard 50/50 IMP + GMP Umami Blend)
Acceptable Daily Intake (ADI)	Not Specified (Quantum Satis)
Composition	50% Disodium Inosinate (E631) + 50% Disodium Guanylate (E627)
Primary Mechanism	Maximum simultaneous allosteric sensitization of oral T1R1+T1R3 umami receptor sites
Common Target Foods	Flavored potato chips, instant noodles, dry soup mixes, processed meats, barbecue sauces
Dietary Compliance	Vegan (Bacterial sugar fermentation), Halal, Kosher
Safety Approval	EFSA Authorized / FDA GRAS

The Global Industrial Seasoning Standard

By formulating MSG with 2–5% E635 (I+G), food scientists achieve a rounded, rich, mouth-coating savory profile that mimics hours of slow meat bone-stock reduction in seconds.