# item.guide
Side-by-Side Comparison Food Additives & E-Numbers

E290: Carbon Dioxide (Carbonation & MAP Gas) vs. E627: Disodium Guanylate (GMP Umami Synergist)

Comparing 2 standards across 9 specifications. 9 key differences identified.

Comparing:
E290: Carbon Dioxide (Carbonation & MAP Gas)
E627: Disodium Guanylate (GMP Umami Synergist)

E290 (Carbon Dioxide / CO2) is an authorized food additive functioning as a carbonating gas, modified atmosphere packaging (MAP) preservative, and cryogenic freezing propellant. INS 290, ADI is Not Limited (Quantum Satis).

View full E290: Carbon Dioxide (Carbonation & MAP Gas) spec sheet →

E627 (Disodium 5'-Guanylate / GMP) is the sodium salt of guanylic acid, a purine nucleotide naturally concentrated in dried shiitake mushrooms. INS 627, ADI is Not Specified, exhibiting massive 8x–30x synergistic umami amplification when paired with MSG.

View full E627: Disodium Guanylate (GMP Umami Synergist) spec sheet →

Specification Comparison Table

9 Parameters
Parameter / Spec
E-Number Code
E290 E627
INS / Codex Number
INS 290 INS 627
Functional Class
Carbonating Gas, Packaging Gas, Preservative, Propellant Flavor Enhancer (Purine Nucleotide Umami Synergist)
Acceptable Daily Intake (ADI)
Not Limited (Quantum Satis) Not Specified (Quantum Satis)
Chemical Formula
CO2 C10H12N5Na2O8P · xH2O
Primary Mechanism
Dissolves in water forming carbonic acid (H2CO3) for effervescence; displaces O2 in packaging to block aerobic mold growth Binds allosteric site on T1R1/T1R3 umami receptor, locking glutamate into the orthosteric binding pocket
Common Target Foods
Carbonated soft drinks, sparkling water, beer, champagne, MAP bagged salads, fresh meats Savory snack seasonings (Doritos, chips), instant ramen noodle seasoning packets, bouillon cubes
Dietary Compliance
100% Vegan, Halal, Kosher Vegan (Microbial fermentation of tapioca/sugar), Halal, Kosher
Safety Approval
EFSA Authorized / FDA GRAS (21 CFR 184.1240) EFSA Authorized / FDA GRAS (21 CFR 172.530)

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