Side-by-Side Comparison
Food Additives & E-Numbers
E150d: Sulfite Ammonia Caramel (Class IV Caramel) vs. E627: Disodium Guanylate (GMP Umami Synergist)
Comparing 2 standards across 10 specifications. 10 key differences identified.
Comparing:
E150d: Sulfite Ammonia Caramel (Class IV Caramel)
E627: Disodium Guanylate (GMP Umami Synergist)
E150d (Class IV Caramel) is prepared by heating carbohydrates with both sulfite and ammonium compounds, creating an intensely dark, negatively charged colloid. INS 150d, group ADI is 300 mg/kg bw/day, the global color standard in cola soft drinks.
E627 (Disodium 5'-Guanylate / GMP) is the sodium salt of guanylic acid, a purine nucleotide naturally concentrated in dried shiitake mushrooms. INS 627, ADI is Not Specified, exhibiting massive 8x–30x synergistic umami amplification when paired with MSG.
Specification Comparison Table
10 Parameters| Parameter / Spec | ||
|---|---|---|
|
E-Number Code
|
E150d | E627 |
|
INS / Codex Number
|
INS 150d | INS 627 |
|
Functional Class
|
Food Color (Deep Brown / Black) | Flavor Enhancer (Purine Nucleotide Umami Synergist) |
|
Acceptable Daily Intake (ADI)
|
300 mg / kg body weight per day (Group ADI for caramel colors) | Not Specified (Quantum Satis) |
|
Primary Mechanism
|
High tinctorial power melanoidin polymers soluble and stable in carbonated phosphoric acid matrix | Binds allosteric site on T1R1/T1R3 umami receptor, locking glutamate into the orthosteric binding pocket |
|
Common Target Foods
|
Cola soft drinks, dark beers/stouts, gravies, pet foods, soy sauce | Savory snack seasonings (Doritos, chips), instant ramen noodle seasoning packets, bouillon cubes |
|
Dietary Compliance
|
Vegan (Sugar/syrup base), Halal, Kosher | Vegan (Microbial fermentation of tapioca/sugar), Halal, Kosher |
|
Safety Approval
|
EFSA Authorized / FDA GRAS (Strictly controlled 4-MEI limits) | EFSA Authorized / FDA GRAS (21 CFR 172.530) |
|
Isoelectric Point & Charge
|
Strong negative colloidal charge (pH 0.5–2.0) preventing precipitation in acid sodas | — |
|
Chemical Formula
|
— | C10H12N5Na2O8P · xH2O |
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