# item.guide
Side-by-Side Comparison Essential Vitamins & Minerals

Sodium (Elemental Na) vs. Vitamin D3 (Cholecalciferol)

Comparing 2 standards across 11 specifications. 11 key differences identified.

Comparing:
Sodium (Elemental Na)
Vitamin D3 (Cholecalciferol)

Sodium is the principal extracellular cation (135–145 mEq/L extracellular), maintaining extracellular fluid volume, plasma osmolality, and driving secondary active transport. Adequate Intake (AI) is 1,500 mg/day, with a Chronic Disease Risk Reduction (CDRR) limit of 2,300 mg/day.

View full Sodium (Elemental Na) spec sheet →

Vitamin D3 is a secosteroid prohormone synthesized endogenously in skin via solar UVB irradiation of 7-dehydrocholesterol. Adult RDA is 600–800 IU (15–20µg), with a Tolerable Upper Limit of 4,000 IU (100µg)/day, regulating systemic calcium absorption and immune gene expression.

View full Vitamin D3 (Cholecalciferol) spec sheet →

Specification Comparison Table

11 Parameters
Parameter / Spec
Nutrient Type
Essential Macromineral / Major Extracellular Electrolyte Fat-Soluble Secosteroid Prohormone
Chemical Forms
Sodium Chloride (NaCl, 39.3% Na by weight), Monosodium Glutamate (MSG, 12.3% Na), Sodium Bicarbonate (27.4% Na) Cholecalciferol (D3 - Animal/Lichen), Ergocalciferol (D2 - Fungi)
Primary Biological Function
Extracellular fluid osmolality maintenance, Blood pressure / volume homeostasis, Action potential depolarization (voltage-gated Na+ channels), SGLT1 glucose cotransport Calcitriol receptor (VDR) activation, intestinal calcium/phosphorus absorption, antimicrobial peptide synthesis
Deficiency Condition
Hyponatremia (Serum Na+ < 135 mmol/L): Cerebral edema, Nausea, Muscle cramps, Seizures, Coma (often exercise-associated from over-hydration) Rickets (children), Osteomalacia (adults), Immune dysregulation
Top Whole Food Sources
Table Salt (NaCl), Cured Bacon, Soy Sauce, Parmigiano-Reggiano, Pickles, Olives, Bread (Processed food accounts for 70% of intake) Sunlight UVB, Atlantic Salmon, Sardines, Egg Yolk, Fortified Milk
Adult Adequate Intake (AI)
1,500 mg / day (Equal to 3.8 g table salt NaCl)
Chronic Disease Limit (CDRR)
2,300 mg / day (Equal to 5.8 g table salt / 1 level teaspoon)
Renal Renin-Angiotensin System
Juxtaglomerular apparatus senses low tubular sodium/pressure, secreting renin to stimulate aldosterone and renal Na+ reabsorption
Adult RDA / RDI
600 – 800 IU / day (15 – 20 µg)
Tolerable Upper Limit (UL)
4,000 IU / day (100 µg) (Endocrine Society: up to 10,000 IU safe)
Target Serum 25(OH)D Level
30 – 50 ng / mL (75 – 125 nmol / L)