E250: Sodium Nitrite (Curing Salt / Anti-Botulism Preservative) vs. E338: Phosphoric Acid (Cola Acidulant)
Comparing 2 standards across 12 specifications. 12 key differences identified.
Sodium nitrite (E250, NaNO2) is an inorganic salt used in cured charcuterie, bacon, and processed meats to inhibit Clostridium botulinum neurotoxin germination, fix cured pink nitrosyl-myoglobin color, and retard lipid autoxidation.
E338 (Phosphoric Acid / H3PO4) is a mineral inorganic acid providing a uniquely dry, tangy, astringent sourness. INS 338, group ADI is 40 mg/kg bw/day (as phosphorus), the quintessential acidulant in cola beverages and processed cheeses.
Specification Comparison Table
12 Parameters| Parameter / Spec | ||
|---|---|---|
|
Chemical Formula
|
NaNO₂ (Molecular Weight: 68.995 g/mol) | H3PO4 (pKa1 2.15) |
|
Functional Class
|
Preservative / Color Retention Agent (Curing Salt) | Acidulant, Acidity Regulator, Sequestrant, Emulsifying Salt |
|
Acceptable Daily Intake (ADI)
|
0–0.07 mg/kg body weight per day (EFSA / JECFA) | 40 mg / kg body weight per day (Group ADI as phosphorus) |
|
INS / E-Number
|
INS 250 / E250 | — |
|
USDA Maximum Residual Level
|
156 ppm in cured meat / 200 ppm in dry cured ham / 120 ppm in bacon with ascorbate | — |
|
Botulism Inhibition Threshold
|
Inhibits Clostridium botulinum spore outgrowth at ≥50–100 mg/kg in presence of NaCl | — |
|
E-Number Code
|
— | E338 |
|
INS / Codex Number
|
— | INS 338 |
|
Primary Mechanism
|
— | Lowers beverage pH to ~2.5 with a clean, sharp, non-fruity tang; retards bacterial outgrowth |
|
Common Target Foods
|
— | Cola soft drinks, root beers, processed cheese melts, sports hydration drinks |
|
Dietary Compliance
|
— | Vegan (Mineral phosphate synthesis), Halal, Kosher |
|
Safety Approval
|
— | EFSA Authorized / FDA GRAS (21 CFR 182.1073) |