# item.guide
Side-by-Side Comparison Food Additives & E-Numbers

E101: Riboflavin (Vitamin B2 Yellow Color) vs. E627: Disodium Guanylate (GMP Umami Synergist)

Comparing 2 standards across 9 specifications. 9 key differences identified.

Comparing:
E101: Riboflavin (Vitamin B2 Yellow Color)
E627: Disodium Guanylate (GMP Umami Synergist)
E101: Riboflavin (Vitamin B2 Yellow Color) →

E101 (Riboflavin / Vitamin B2) is an authorized yellow food colorant and essential micronutrient produced via microbial fermentation of Ashbya gossypii. INS 101(i), ADI is 0.5 mg/kg bw/day, commonly used to fortify cereals and color sauces.

View full E101: Riboflavin (Vitamin B2 Yellow Color) spec sheet →
E627: Disodium Guanylate (GMP Umami Synergist) →

E627 (Disodium 5'-Guanylate / GMP) is the sodium salt of guanylic acid, a purine nucleotide naturally concentrated in dried shiitake mushrooms. INS 627, ADI is Not Specified, exhibiting massive 8x–30x synergistic umami amplification when paired with MSG.

View full E627: Disodium Guanylate (GMP Umami Synergist) spec sheet →

Specification Comparison Table

9 Parameters
Parameter / Spec
E101: Riboflavin (Vitamin B2 Yellow Color)
E627: Disodium Guanylate (GMP Umami Synergist)
E-Number Code
E101 E627
INS / Codex Number
INS 101(i) INS 627
Functional Class
Food Color (Yellow-Orange), Nutrient Fortificant Flavor Enhancer (Purine Nucleotide Umami Synergist)
Acceptable Daily Intake (ADI)
0.5 mg / kg body weight per day Not Specified (Quantum Satis)
Chemical Formula
C17H20N4O6 C10H12N5Na2O8P · xH2O
Primary Mechanism
Yellow chromophore acting as precursor to flavin coenzymes (FAD/FMN) Binds allosteric site on T1R1/T1R3 umami receptor, locking glutamate into the orthosteric binding pocket
Common Target Foods
Fortified breakfast cereals, baby foods, pasta, dairy desserts, energy drinks Savory snack seasonings (Doritos, chips), instant ramen noodle seasoning packets, bouillon cubes
Dietary Compliance
100% Vegan (Microbial fermentation), Halal, Kosher Vegan (Microbial fermentation of tapioca/sugar), Halal, Kosher
Safety Approval
EFSA Authorized / FDA GRAS (21 CFR 73.450) EFSA Authorized / FDA GRAS (21 CFR 172.530)

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