# item.guide

Zinc (Elemental Zn)

Essential Vitamins & Minerals · 8 specs

Direct Answer

Zinc is an essential trace mineral serving as a structural component in over 2,000 transcription factor 'zinc finger' proteins and catalytic cofactor for 300+ enzymes. Adult RDA is 11mg (men) / 8mg (women), with a Tolerable Upper Limit of 40mg/day.

Source: NIH Office of Dietary Supplements / WHO · Last reviewed Aug 28, 2026

Specs

Nutrient Type Essential Trace Mineral
Adult RDA / RDI 11 mg / day (Men) / 8 mg / day (Women)
Tolerable Upper Limit (UL) 40 mg / day (Chronic excess induces copper deficiency)
Chemical Forms Zinc Picolinate, Bisglycinate, Gluconate, Sulfate, Oxide
Primary Biological Function Zinc finger DNA transcription factors, Superoxide Dismutase (SOD1), Carbonic anhydrase, Testosterone synthesis, Phagocytosis
Deficiency Condition Impaired immunity, Hypogonadism, Delayed wound healing, Alopecia, Loss of taste/smell (Anosmia/Ageusia)
Top Whole Food Sources Eastern Oysters, Beef Chuck, Crab, Pumpkin Seeds, Hemp Hearts, Chickpeas
Copper Balance Warning High zinc stimulates intestinal metallothionein which binds copper, risking microcytic anemia if copper is unsupplemented

Zinc Finger Domains & Gene Expression

Zinc is uniquely required for the structural conformation of 'zinc finger' motifs in nuclear steroid hormone receptors, modulating gene expression for testosterone, thyroid hormones, and vitamin D.

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